An increasing number of fly lines are being developed which faithfully model various aspects of human disease and human health-related processes. Listed on these pages (see links below) are fly stocks available at Bloomington which can be used to study a variety of human diseases as well as human health-related subjects such as metabolism. In addition, we also list stocks useful for studying genes and pathways associated with these processes.

IMPORTANT - In some instances, not every available stock for a particular gene is listed. In general - 1) we list all available expression constructs, 2) in cases where there were several insertion and non-insertion-based alleles available, we list only those which appear to be widely used in the literature, and 3) we did not, for the most part, include insertion-based alleles for which there are no published data available. Researchers looking for additional tools (for instance, insertions from which to make deletions) should make sure to look at the full list of available insertions and mutations on the relevant gene page at FlyBase.

These pages are a work in progress (additional pages will be added as stock lists are assembled) and we welcome any and all input. If you see any errors, notice relevant genes or stocks we have missed, have any advice or suggestions on additional diseases to include, or have human disease-related stocks you would like to make available at the BDSC, please contact us.

Download a csv or Excel (xlsx) file containing all the disease gene stocks found on these pages with a column that includes the full genotype of the stock.

Outside fly resources:
Homophila - A database of OMIM-derived human disease genes and their fly homologs
LAMHDI - A database of animal strains and stocks (including Drosophila) associated with human disease
Bonini neurodegeneration list - A list of fly mutants with neurodegenerative phenotypes from the Bonini lab
Thummel metabolism gene list - A list of genes predicted to function in metabolic pathways from the Thummel lab.