Transpositions in Bloomington stocks
Updated September 15, 2015
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Introduction

A transposition is generated by three chromosomal breakpoints and the movement of a chromosomal segment to a new position. A transposition can be separated into deletion and duplication components.

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Transpositions can be interchromosomal as shown in the figure, or they can be intrachromosomal so that the deletion and duplication components remain linked.

In general, transposition stocks in the Bloomington collection are maintained because the deletion and/or duplication chromosomes are useful for experiments, or because one of the breakpoints disrupts a gene.

Transpositions useful for their deletion and/or duplication components
Transpositions that cause mutations
Incidental transposition

Transpositions useful for their deletion and/or duplication components

The following stocks have deletion and/or duplication components that can be useful in gene mapping, complementation and mutation rescue experiments. These stocks are used more frequently for their duplication components; consequently, they are also listed among cytologically defined duplication stocks.

  Symbol Stk # Genotype Breakpts
1 Tp(1;2)rb[+]71g 909 Tp(1;2)rb[+]71g, ct[6] v[1]/C(1)DX, y[1] f[1] 3F3;5E8 into 23A1-5
2 Tp(1;2)r[+]75c 3217 C(1)M4, y[2]; Tp(1;2)r[+]75c, sl[3]/CyO 14B13;15A9 into 35DE
3 Tp(1;2)sn[+]72d 910 Tp(1;2)sn[+]72d, f[1] car[1]/C(1)DX, y[1] f[1]; Dp(?;2)bw[D], bw[D] 7A8;8A5 into 58E
4 Tp(1;2)v[+]65b 930 Tp(1;2)v[+]65b, lz[50e] v[+65b]/C(1)DX, y[1] w[1] f[1] 9F12-13;11A6-9 into 40-41
5 Tp(1;2)w-ec 1319 Tp(1;2)w-ec, ec[64d] cm[1] ct[6] sn[3]/C(1)DX, y[1] w[1] f[1] 3C2;3E8 into 37D
6 Tp(1;3)sta 844 Tp(1;3)sta, sta[1]: ss[sta]/FM3 1E1;2B3-4 into 89C1-2
7 Tp(1;3)v[+]74c 4245 Tp(1;3)v[+]74c/FM7a 9E3;11B12 into 80-81
8 Tp(2;3)DX11 4118 Tp(2;3)DX11, l(2)43Bb[3] cn[1] bw[1] sp[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 41;43B1-3 into 80
9 Tp(2;3)P 1643 Tp(2;3)P, Pale[1], dpy[ov1] b[1] cn[1] Gull[1]: e[1]/CyO; TM1 58E3-4;60D14-E2 into 96B5-C1
10 Tp(3;Y)P92 4244 Dp(3;1)P68, y[1]/FM6; Tp(3;Y)P92, p[p] hb[D1] 84D10-11;85A1-3 into Y
11 Tp(3;Y)ry506-85C 1534 Tp(3;Y)ry506-85C/MKRS 87D1-2;88E5-6 into Y

Transpositions that cause mutations

The following stocks are maintained because at least one transposition breakpoint disrupts a gene.

  Symbol Gene allele Stk # Genotype Breakpts
1 Tp(1;3)sta ss[sta] 844 Tp(1;3)sta, sta[1]: ss[sta]/FM3 1E1;2B3-4 into 89C1-2
2 Tp(1;3)sta sta[1] 844 Tp(1;3)sta, sta[1]: ss[sta]/FM3 1E1;2B3-4 into 89C1-2
3 Tp(2;2)pk-sple[22] pk[pk-sple-22] 5887 Tp(2;2)pk-sple[22], b[1] l(2)42Eb[pk-sple-22] pk[pk-sple-22] cn[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 41EF;42F3 into 43A1
4 Tp(2;2)pk-sple[26] pk[pk-sple-26] 4118 Tp(2;3)DX11, l(2)43Bb[3] cn[1] bw[1] sp[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 29F;58E;42F;45A (complex intrachromosomal rearrangement)
5 Tp(2;2)pk-sple[26] pk[pk-sple-26] 4130 In(2R)DX8, Dscam1[17] cn[1] bw[1] sp[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 29F;58E;42F;45A (complex intrachromosomal rearrangement)
6 Tp(2;2)pk-sple[26] pk[pk-sple-26] 5887 Tp(2;2)pk-sple[22], b[1] l(2)42Eb[pk-sple-22] pk[pk-sple-22] cn[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 29F;58E;42F;45A (complex intrachromosomal rearrangement)
7 Tp(2;2)pk-sple[26] pk[pk-sple-26] 8889 Df(2R)sple-D1, b[1] cn[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 29F;58E;42F;45A (complex intrachromosomal rearrangement)
8 Tp(2;2)pk-sple[26] pk[pk-sple-26] 44232 pk[sple-4] cn[1] bw[1] sp[1]/CyO, Tp(2;2)pk-sple[26], pk[pk-sple-26] 29F;58E;42F;45A (complex intrachromosomal rearrangement)
9 Tp(2;3)P Gull[1] 1643 Tp(2;3)P, Pale[1], dpy[ov1] b[1] cn[1] Gull[1]: e[1]/CyO; TM1 58E3-4;60D14-E2 into 96B5-C1
10 Tp(2;3)P Pale[1] 1643 Tp(2;3)P, Pale[1], dpy[ov1] b[1] cn[1] Gull[1]: e[1]/CyO; TM1 58E3-4;60D14-E2 into 96B5-C1
11 Tp(3;2)Antp[Ctx] Antp[Ctx] 2251 Tp(3;2)Antp[Ctx], Antp[Ctx] Sb[sbd-2]/TM1 83C8-9;84B2-3 and 84B2-3;85E4-5 into 35B3-4
12 Tp(3;3)Vno Abd-B[Vno] 3717 Df(1)bb74, y[1] pn[1] cv[1] m[1] f[1]/FM7a; TM2/Tp(3;3)Vno, Abd-B[Vno], Vno[1]; sv[spa-pol] 89E;93F & 93F;94A into 96F11-14
13 Tp(3;3)Vno Vno[1] 3717 Df(1)bb74, y[1] pn[1] cv[1] m[1] f[1]/FM7a; TM2/Tp(3;3)Vno, Abd-B[Vno], Vno[1]; sv[spa-pol] 89E;93F & 93F;94A into 96F11-14
14 Tp(3;Y)82Fd[1] mtd[1] 4877 Tp(3;Y)82Fd[1], mwh[1] mtd[1] red[1] e[4]/TM3, Sb[1] 82F3-11;98F8-14 into Y

Incidental transposition

We have one stock where the transposition is somewhat irrelevant. The stock is maintained for Df(2R)pk78k. The intrachromosomal transposition Tp(2;2)CA30 is present and the deletion and duplication components could potentially be separated and used in experiments, but, basically, it is incidental.

  Symbol Stk # Genotype Breakpts
1 Tp(2;2)CA30 1594 Df(2R)pk78k, Tp(2;2)CA30, sp[1]/CyO 26C1;27D1 into 34A4-34B1