Duplications
Updated February 3, 2015
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  Interchromosomal duplications
X chromosome
  • Molecularly defined Y-linked duplications - The duplicated X chromosome segments in this set range from more than 160 genes down to only a few genes and they are arranged in nested sets. The breakpoints provide mapping resolution of a median of nine genes. This is the most convenient set to use for duplication mapping X-linked mutations.

  • Molecularly defined transgenic duplications - The duplicated segments in this set were generated by transgenic methods and contain around 5 to 20 genes. Most are inserted on the third chromosome. This set may provide higher mapping resolution in some regions and may be more convenient for duplicating particular genes.

  • Cytologically defined duplications - These are older duplications generated by irradiation and characterized primarily by polytene chromosome cytology. They vary in size and insertion site, but most are much larger than transgenic duplications. Typically, these duplications are now used to supplement the sets above or when one needs a duplicated segment inserted at an alternative site.
    Additional X Chr lists
     
  • X Chromosome Duplication Kit - To simplify the initial mapping of X-linked mutations, we have assembled this kit to provide complete coverage with the fewest molecularly defined duplications from the sets above.
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  • All molecularly defined X chromosome duplications - A list of all X duplications with sequence-mapped endpoints regardless of source or insertion site.

Second chromosome
Third chromosome
Fourth chromosome
  Intrachromosomal duplications
We list intrachromosomal duplications separately because they are primarily used for changing the dosages of genes and are less useful for gene mapping and rescue experiments. All have been characterized by polytene cytology. The lists below provide efficient coverage of the indicated chromosome with a subset of intrachromosomal duplications: