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Sleep Inbred Panel stocks

The Sleep Inbred Panel (SIP) is a set of recombinant inbred lines generated by Susan Harbison and colleagues to investigate the genetic basis of sleep duration. As shown in the diagram below and described in detail in this downloadable document, the lines are homozygous or near-homozygous stocks established from populations selected for long and short periods of night sleep.

Mating scheme for generating Sleep Inbred Panel lines

The SIP lines were inbred from four populations artificially selected for extreme long or short sleep. Ten fully sequenced Drosophila Genetic Reference Panel (DGRP) stocks were used as the starting genetic material for the artificial selection procedure. The goal was to preserve the extreme long- and short-sleeping phenotypes obtained via artificial selection for further correlational and transcriptional analyses.

Information on the full genome sequences of the SIP lines will be available in a forthcoming paper.

Note that we will likely distribute these stocks for only a limited period. They went into public distribution in October 2017. We will assess demand in a couple of years and may discard them at that time.

Stk # Genotype
  Recombinant inbred lines selected for short sleep duration
76281 SIP_S1_1
76282 SIP_S1_2
76283 SIP_S1_3
76284 SIP_S1_4
76285 SIP_S1_5
76286 SIP_S1_6
76287 SIP_S1_7
76288 SIP_S1_8
76289 SIP_S1_9
76290 SIP_S1_10
76300 SIP_S2_1
76301 SIP_S2_2
76302 SIP_S2_3
76303 SIP_S2_4
76304 SIP_S2_5
76305 SIP_S2_6
76306 SIP_S2_7
76307 SIP_S2_8
76308 SIP_S2_9
76309 SIP_S2_10
  Recombinant inbred lines selected for long sleep duration
76271 SIP_L1_1
76273 SIP_L1_3
76274 SIP_L1_4
76275 SIP_L1_5
76276 SIP_L1_6
76277 SIP_L1_7
76278 SIP_L1_8
76279 SIP_L1_9
76280 SIP_L1_10
76291 SIP_L2_1
76292 SIP_L2_2
76293 SIP_L2_3
76294 SIP_L2_4
76295 SIP_L2_5
76296 SIP_L2_6
76297 SIP_L2_7
76298 SIP_L2_8
76299 SIP_L2_10