The importation and interstate transportation of DNA clones or transgenic flies containing sequences from “select agents” are strictly regulated. Select agents are specific biological agents and toxins that have the potential to pose a severe threat to public, animal or plant health and have been chosen for special regulation (see the CDC Select Agent Program, the APHIS Agricultural Select Agent Program and the National Select Agent Registry). To our knowledge, the only Drosophila constructs incorporating such sequences are UAS-ricin A constructs used in cell ablation studies. The importation of transgenic flies carrying sequences from select agents requires approval from multiple federal agencies in addition to the USDA and should be attempted only with the approval and help of biosafety and legal officials at your institution.