Werner syndrome is a disorder characterized by accelerated symptoms of aging including graying of hair, diabetes, cardiovascular disease, sarcomas, atherosclerosis, and cataracts. Werner syndrome is caused by mutations in the DNA helicase gene, RecQ (aka WRN), which are believed to lead to hyper-recombination and DNA replication defects. Fly stocks in the Bloomington collection that can be used to study Werner syndrome are listed here.

General Information links for Werner syndrome:

• OMIM
• NIH's Genetics Home Reference - includes links for a GHR page on WRN